Delta-Sleep-Inducing Peptide (DSIP) was first proposed as a sleep-peptide and this remains the prevalent impression of its function. Since normal people spend about one-third of their lifetime sleeping (about 25 years), it is rather surprising that the phenomenon of sleep and its purpose, which is still in question, has been long overlooked as a topic of scientific interest. A decisive step forward was made between
Read MoreKisspeptins (formerly known as metastin) are peptides encoded by KISS1. The gene was first discovered in 1996, in Hershey, PA, USA, and was subsequently named after Hershey’s chocolate kisses. The peptide product of KISS1 is a 145 amino acid peptide that is cleaved into four shorter peptides: kisspeptin-54, kisspeptin-14, kisspeptin-13, and kisspeptin-10 (the numbers denote how many amino acids in each). All these isoforms activate the
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