Tesofensine
Tesofensine is a triple monoamine reuptake inhibitor, dispensed here as a compounded capsule at 0. 5mg or 1mg. It is a non-injectable option in metabolic care. Compounded medications are not FDA-approved, and a licensed provider reviews your history and medication list before prescribing.
Pharmacy shipping: $20 added once per medication order.
About this treatment
An oral approach being studied for appetite control.
Tesofensine research looks at hunger, fullness and weight management through brain signaling. Understanding that approach helps you discuss an oral option and the monitoring it would require.
A different way of working with appetite
Tesofensine blocks the reuptake of serotonin, noradrenaline and dopamine, three chemical messengers involved in brain signaling. Researchers are studying how this action affects appetite and eating behavior. It works through a different drug pathway from GLP-1 medicines.
What the fullness research explores
Early human studies reported greater fullness and satiety, along with less anticipated food intake. These are the appetite changes researchers have explored when studying tesofensine for weight management.
Keep pulse, sleep and tolerability in view
Human trials reported increased heart rate, dry mouth, digestive symptoms and insomnia. Your medication list, cardiovascular history and sleep symptoms matter when discussing this medicine. Report a racing heartbeat or significant changes in sleep or mood; chest pain or fainting needs prompt medical attention.
Research and product information
Tesofensine has no FDA-approved U.S. product. IAM lists compounded capsules, which the cited studies did not test. The 2008 obesity trial carries a Lancet Expression of Concern; appetite analyses from that research program also need to be read with this limitation in mind.
- Tesofensine: human study of appetite sensations
- Tesofensine: randomized phase 2 obesity trial
- The Lancet: Expression of Concern about the tesofensine obesity trial
Sources checked .
Your path to Tesofensine
Complete the assessment
Share your weight history, current medications, and goals in the patient portal.
Provider review
A licensed provider checks for interactions and decides what to prescribe.
Care coordination
Your care team coordinates the prescription after provider approval.
About this treatment
What it is
Tesofensine is a triple monoamine reuptake inhibitor taken by mouth. IAM dispenses it as a compounded capsule in two strengths, and your provider decides which is prescribed.
Who it's for
Patients whose provider decides an oral option fits better than an injection, or who are not candidates for a GLP-1. That decision follows a review of your history and current medications.
Forms we dispense
Capsule 0.5mg · 1mg
A licensed provider reviews your history and requests labs when clinically appropriate before prescribing.
Prescriptions are coordinated with our licensed US pharmacy partner, with dosing supplies included when needed.
We do not sell pharmaceuticals online. Every prescription comes after a full provider review.
