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MOTS-C

MOTS-C, an unlabeled amber injectable vial

MOTS-C is a mitochondrial-derived peptide, dispensed here as a compounded 10mg/mL injectable in a 5mL vial. Compounded medications are not FDA-approved and the research behind this one is early. A licensed provider reviews your history before prescribing.

Compounded injectable at 10mg/mL, 5mL vial
A peptide encoded in mitochondrial DNA
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Prescription required · Provider review and syringes included

About this treatment

Explore the link between movement and metabolism.

MOTS-C is being studied for its role in how muscles use energy and respond to activity. Your IAM consultation connects that research with your metabolic health, daily routine and the goals that matter to you.

A signal from your mitochondria

Mitochondria help cells use energy. MOTS-C is a short peptide encoded within mitochondrial DNA, with a research focus on communication between these structures and the rest of the cell. One pathway of interest is AMPK, a cellular energy sensor involved in glucose use and responses to metabolic stress.

[1]

Why muscle and metabolic health attract interest

MOTS-C research looks at insulin sensitivity, skeletal muscle and adaptation to physical activity. Researchers have also measured changes in the body's own MOTS-C after exercise. Together, these topics explain the interest in its relationship with movement, metabolism and aging.

[1][2]

Bring your goals into the conversation

Tell your care team whether you want to discuss metabolic health, exercise tolerance or changes in everyday activity. Reviewing your health history and current routine helps keep the conversation specific. Your provider can discuss the preparation, the research behind it and how follow-up would fit your overall care.

[2][3]

Research and product information

Treatment research is primarily laboratory and animal work. The human exercise study measured naturally occurring MOTS-C, not injections. Human benefit and long-term safety of the compounded injectable are not established; FDA identifies limited safety information and potential immune-reaction concerns.

  1. Lee et al. MOTS-C, mitochondrial signaling and metabolic regulation (2015)
  2. Reynolds et al. MOTS-C, exercise and muscle homeostasis (2021)
  3. FDA: safety information for certain bulk substances used in compounding

Sources checked .

Your path to MOTS-C

01

Complete the assessment

Share your health history and goals in the patient portal.

02

Provider review

A licensed provider decides whether MOTS-C is appropriate for your situation.

03

Care coordination

Your care team coordinates the prescription and dosing supplies after provider approval.

About this treatment

What it is

A peptide encoded in mitochondrial rather than nuclear DNA, dispensed here as a compounded injectable. Research is ongoing, and your provider will go over what is and is not known.

Who it's for

Adults whose provider decides a newer compounded peptide fits their plan, and who understand the evidence is early.

Forms we dispense

Injectable 10mg/mL

Real provider oversight

A licensed provider reviews your history and requests labs when clinically appropriate before prescribing.

Licensed pharmacy coordination

Prescriptions are coordinated with our licensed US pharmacy partner, with dosing supplies included when needed.

Only when appropriate

We do not sell pharmaceuticals online. Every prescription comes after a full provider review.

Frequently asked questions