Ibutamoren (MK-677)
Ibutamoren, also called MK-677, is an orally active ghrelin mimetic. The pharmacy dispenses it as a compounded 25mg capsule, 60 per supply. Compounded medications are not FDA-approved, and a licensed provider reviews your history before prescribing.
Pharmacy shipping: $20 added once per medication order.
About this treatment
Understand an oral approach to growth hormone signaling.
Ibutamoren, also called MK-677, acts on the ghrelin receptor and has been studied for its effects on growth hormone and body composition. IAM lists a compounded capsule, making your medical history, metabolic health and goals central to the discussion.
A small molecule that acts on a hormone signal
Ibutamoren is a small molecule rather than a peptide. It mimics part of ghrelin's signaling by activating its receptor, which can stimulate the body's release of growth hormone and raise IGF-1. It is taken by mouth, so its research differs from that of injected growth hormone and other injectable secretagogues.
Body composition is more than muscle performance
Fat-free mass includes muscle, water and other tissues. Researchers studying ibutamoren have measured body composition alongside grip or limb strength, physical function and blood sugar. For a patient, goals such as getting up from a chair, maintaining activity or recovering from training need their own assessment. A laboratory or scan result tells only part of that story.
Bring metabolic and heart health into the review
Tell your provider about diabetes, swelling, heart disease and medicines that affect blood sugar or fluid balance. Ask what symptoms and lab results would be followed if a capsule is considered. New shortness of breath, rapidly increasing swelling or chest symptoms require prompt medical assessment rather than waiting for a routine follow-up.
Research and product information
A trial in older adults found increased fat-free mass without improved strength or function. Ibutamoren is not FDA-approved. FDA flags a heart-failure safety signal in a separate hip-fracture trial; appetite, fluid retention and blood-sugar effects also matter to individual risk.
- Nass et al. MK-677, body composition and clinical outcomes in older adults: randomized trial (2008)
- FDA: ibutamoren safety information for compounding
Sources checked .
Your path to Ibutamoren (MK-677)
Complete the assessment
Share your recovery goals, sleep, and health history in the patient portal.
Provider review
A licensed provider decides whether MK-677 fits your situation and sets the strength.
Care coordination
Your care team coordinates the prescription after provider approval.
About this treatment
What it is
An orally active ghrelin receptor agonist, compounded here as a capsule. It is not an FDA-approved product.
Who it's for
Adults whose provider decides an oral compound in this class fits their plan, after reviewing their history and labs.
Forms we dispense
Capsule 25mg
A licensed provider reviews your history and requests labs when clinically appropriate before prescribing.
Prescriptions are coordinated with our licensed US pharmacy partner, with dosing supplies included when needed.
We do not sell pharmaceuticals online. Every prescription comes after a full provider review.
