Dihexa

Dihexa is an investigational peptide-like compound derived from angiotensin IV research. The pharmacy lists a compounded 10mg capsule. It is not FDA-approved, published human evidence is very limited, and a licensed provider reviews those limitations and your health history before deciding whether it is appropriate.
Pharmacy shipping: $20 added once per medication order.
About this treatment
A closer look at Dihexa and brain signaling.
Dihexa is an investigational peptide-like compound developed to explore brain-cell signaling. If memory or attention is your concern, your IAM visit starts with how it affects your day and what you want help with.
The idea behind Dihexa
Dihexa originated from work on chemically modified relatives of angiotensin IV. The development program explored nerve-cell communication and learning, aiming to create a molecule suitable for further cognitive research. That background explains its place in discussions of emerging brain-health approaches.
Start with what you have noticed
Specific examples make a cognitive-care conversation more useful. Describe when a memory problem began, how often it happens and which daily tasks are affected. Your clinician can review your symptoms, medicines and health history, then decide which assessment fits the concern.
A capsule considered in clinical context
IAM lists Dihexa as a compounded capsule. Before making a decision, your provider can explain the research background and discuss the care options relevant to your symptoms. Agree on the purpose of follow-up and the changes that should prompt a review.
Research and product information
Human cognitive benefit and long-term safety have not been established. The 2013 foundational study has a journal Notice of Concern; the 2014 mechanism paper was retracted in 2025. These publication concerns are material to interpreting older claims about Dihexa.
- Dihexa development study, subject to a journal Notice of Concern (2013)
- Journal Notice of Concern for the 2013 Dihexa study (2021)
- Dihexa mechanism paper and its journal retraction notice (2014; retracted 2025)
- NIH MedlinePlus: assessment of memory changes
Sources checked .
Patient reviews
What patients say about IAM.
The peptide protocol has enhanced my recovery time significantly.
As a trainer, I need to perform at my best daily.
Emil and his team are 100% committed to his customers and their health
Emil and his team are 100% committed to his customers and their health. I was sending him messages from a FB post I saw him make long before I was a client and he would always respond with thoughtful and helpful responses. He would also tell me that I didn't need to be a customer for him to help! He's that passionate about helping people! I have since become a client and everything I have gotten from IAMHRT, from peptides to TRT meds, has put me on a better path to feeling great and being healthier. These guys are the real deal and the prices are also fantastic. I highly recommend this company and this man!
The peptide therapy has been amazing for my recovery and overall wellness.
I sleep better and recover faster from workouts.
Written by IAM patients in their own words, with only spelling corrected. Individual results vary.
Your path to Dihexa
Complete the assessment
Share your cognitive concerns, goals, health history, and current medications.
Provider review
A licensed provider discusses the limited human evidence and determines whether Dihexa is appropriate.
Care coordination
Your care team coordinates the compounded prescription and clinically appropriate follow-up after approval.
About this treatment
What it is
Dihexa is an investigational peptide-like molecule originating from angiotensin IV research. IAM's pharmacy catalog lists it as a compounded capsule, not an FDA-approved product.
Who it's for
Adults who want to discuss an investigational cognitive-care option with a provider and understand that published human evidence is very limited.
Forms we dispense
Capsule 10mg
A licensed provider reviews your history and requests labs when clinically appropriate before prescribing.
Prescriptions are coordinated with our licensed US pharmacy partner, with dosing supplies included when needed.
We do not sell pharmaceuticals online. Every prescription comes after a full provider review.

