Bremelanotide
Bremelanotide, also known as PT-141, is a melanocortin receptor agonist, a different class from the PDE5 inhibitors. The pharmacy dispenses it as a 20mg preservative-free injectable, a 2mg/mL nasal spray and a 1mg capsule, compounded to order. Compounded medications are not FDA-approved, and your provider chooses the form after reviewing your history.
Pharmacy shipping: $20 added once per medication order.
About this treatment
A closer look at low sexual desire.
Bremelanotide, also called PT-141, is studied for low sexual desire that causes distress. Understanding whether your concern is desire, arousal, erection or discomfort helps your care team guide a more useful conversation.
Understand the change in desire
Low desire can mean different things to different people. A consultation looks at when the change began, whether it is persistent and how it affects you. Health conditions, medicines, relationship context and comfort all help shape an appropriate care plan.
What improved in the clinical studies
In the RECONNECT trials, women receiving bremelanotide reported improvements in sexual desire and less distress related to low desire compared with placebo. The studies assessed the experience of desire itself, giving patients and clinicians a way to discuss a change that matters personally.
A different pathway from erection medicines
Bremelanotide activates melanocortin receptors involved in sexual-response signaling. Sildenafil and tadalafil act through a different pathway that supports erectile blood flow. Identifying the main concern helps your provider discuss which approach is relevant.
Research and product information
Evidence for improved desire and related distress comes from subcutaneous Vyleesi in premenopausal women with acquired, generalized HSDD. IAM's compounded injectable, nasal spray and capsule are different preparations; those trial results do not establish equivalent benefits for these forms, men or postmenopausal women.
- Vyleesi: prescribing information and patient information
- RECONNECT: two randomized phase 3 bremelanotide trials
- Cialis: tadalafil prescribing information and PDE5 mechanism
Sources checked .
Your path to Bremelanotide
Complete the assessment
Share your concerns and health history in the patient portal.
Provider review
A licensed provider decides whether bremelanotide fits and picks your delivery form.
Care coordination
Your care team coordinates the prescription and dosing supplies after provider approval.
About this treatment
What it is
A melanocortin receptor agonist, compounded here in three forms. It is a different class from tadalafil and sildenafil, which are PDE5 inhibitors.
Who it's for
Adults whose provider decides a melanocortin agonist fits, after reviewing their history, blood pressure and current medications.
Forms we dispense
Injectable PF 20mg · Nasal spray 2mg/
A licensed provider reviews your history and requests labs when clinically appropriate before prescribing.
Prescriptions are coordinated with our licensed US pharmacy partner, with dosing supplies included when needed.
We do not sell pharmaceuticals online. Every prescription comes after a full provider review.
